Northwest District

The document provides a comprehensive scientific overview of thiols and their biotransformation, particularly in the context of brewing. It details the chemistry, detection methods, and concentrations of thiols in raw materials, emphasizing their characteristics, reactivity, and the analytical techniques used for their detection, such as Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Sulfur Chemiluminescence Detector (GC-SCD). The text also explores the biotransformation of bound thiols during fermentation, identifying enzyme targets and pathways, while presenting data on thiol concentrations in various brewing ingredients, thereby highlighting the need for further research in this area.